Elizabeth Edwards and Radhakrishnan Mahadevan of the University of Toronto are developing computational models using microbial genomes and metagenomes to uncover metabolic interactions in complex anaerobic microbial communities. They will identify and validate metabolic gaps pointing to metabolites exchanged among an anaerobic subsurface mixed microbial community that contains microbes used for bioremediation of toxic chlorinated solvents. This project aims to boost the efficiency of dechlorination in groundwater remediation, and resolve metabolic gaps in genome-scale models at the microbial community level.
